The Ampney Brook, a tributary of the River Thames, flows through the village, which is near the smaller villages of Ampney St Mary and Ampney St Peter, and about three miles east of Cirencester. The village takes its name (Latin for "Ampney of the Cross") from the brook and the 15th-century cross in the churchyard of the parish church, the Church of the Holy Rood. This church is a Grade-I-listed building and the cross is also Grade-I listed. The church has Saxon foundations, some Norman structure and some features built in later periods. The tower dates from the 15th century.
In 1671 when households were assessed for the hearth tax, Ampney House was described as a "modest mansion in a park" and had ten hearths, while the Lloyds, the only other gentry family in the village, had seven hearths. Of the remaining dwellings with hearths, ten were exempt on the grounds of poverty while the remaining households each had a single hearth. At that time, apart from the lord of the manor and the Lloyds, the inhabitants of the parish were mostly their tenants; labourers, husbandmen and craftsmen, each with their own patch of ground to supply the family with food.
- Concise Road Atlas of Britain. AA Publishing. 2016. p. 30. ISBN 978-0-7495-7743-8.
- "Church of the Holy Rood, Ampney Crucis". British Listed Buildings. http://www.britishlistedbuildings.co.uk/en-129635-church-of-the-holy-rood-ampney-crucis-gl#.V8R5M63GD6g. Retrieved 29 August 2016.
- David Rollison (2011). Commune, Country and Commonwealth: The People of Cirencester, 1117-1643. Boydell & Brewer Ltd. pp. 221–222. ISBN 978-1-84383-671-1. https://books.google.com/books?id=XExS0__A2rUC&pg=PA221.
- "The Domesday Book online". Gloucestershire A-F. http://www.domesdaybook.co.uk/gloucestershire1.html. Retrieved 29 August 2016.
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